AFDIEX 5MG contains Glibenclamide which belongs to the group of medicines called Antidiabetic agents. It is used to treat type 2 diabetes mellitus, when diet and physical exercise alone have not been able to control the blood sugar levels.Type 2 diabetes is a disease in which blood sugar levels are too high and the body either doesn't produce enough insulin, or it resists insulin. Symptoms include increased thirst, hunger, urination, feeling tired, blurred vision, numbness or tingling in the feet or hands, sores that do not heal, weight loss.
Glibenclamide lowers blood sugar by helping the pancreas to produce insulin (natural substance needed to break down sugar in the body) so that the body can use insulin efficiently. This will only help lower blood sugar in bodies which produce insulin naturally. Along with this treatment, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, not skipping meals & regular exercise. Prior to the treatment, your doctor may want you to take several blood tests to understand your existing condition.
Avoid consumption of alcohol during treatment with AFDIEX 5MG, as it may worsen the side effects. Before taking AFDIEX 5MG, inform your doctor if you suffer from low blood sugar attack, have G6PD deficiency, recovering from an operation or stress. AFDIEX 5MG is not recommended for use in patients who have porphyria, insulin dependent diabetes, diabetic ketoacidosis, diabetic coma, serious problems with kidneys, liver, adrenal glands, or pituitary glands. AFDIEX 5MG is not recommended for use in pregnant and breastfeeding women. AFDIEX 5MG is also not recommended for use in children. Consult your doctor before taking it. The most common side effects of taking AFDIEX 5MG are low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin.
USES OF AFDIEX 5MG
Treats type 2 diabetes mellitus
HOW AFDIEX 5MG WORKS
AFDIEX 5MG lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This will only help lower blood sugar in bodies which produce insulin naturally.
DIRECTIONS FOR USE
Take AFDIEX 5MG as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF AFDIEX 5MG
COMMON
Dizziness
Sweating
Palpitations
Hunger pangs
Dry mouth and skin
RARE
Lower blood sugar than normal (hypoglycemia)
Decrease in the number of platelets (which increases risk of bleeding or bruising), white blood cells (which makes infections more likely), red blood cells (can pale the skin and cause weakness, breathlessness)
Stop taking AFDIEX 5MG and contact your doctor immediately if you experience any of the following side effects:
Allergic (hypersensitivity) reactions (swelling of the lips, face, throat or tongue, skin rash, itching, hives and increased sensitivity to the sun, inflammation of blood vessels, serious reactions like difficulty breathing, fall in blood pressure and sometimes shock)
Abnormal liver function including yellowing of the skin and eyes (jaundice)
Problems with the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure
Severe hypoglycemia including loss of consciousness or seizures
WARNING & PRECAUTIONS
PREGNANCY
AFDIEX 5MG is not recommended for use in pregnancy. Consult your doctor before taking it.
BREASTFEEDING
AFDIEX 5MG is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Avoid driving and using machines while taking AFDIEX 5MG as it may reduce your ability to concentrate or react if your blood sugar is lowered (hypoglycemia).
ALCOHOL
Avoid drinking alcohol while taking AFDIEX 5MG as it may increase or decrease the blood sugar levels lowering the action of AFDIEX 5MG.
KIDNEY
AFDIEX 5MG is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with severe kidney disorder. Consult your doctor before taking.
LIVER
AFDIEX 5MG is not recommended for use in patients with severe liver disease. It should be used with caution in patients with severe liver disorder. Consult your doctor before taking.
ALLERGY
Do not take AFDIEX 5MG if you are allergic to Glibenclamide.
HEART DISEASE
AFDIEX 5MG is not recommended for use in patients with coronary artery disease. AFDIEX 5MG should be used with caution in patients with other heart diseases. Consult your doctor before taking it.
OTHERS
AFDIEX 5MG is not recommended for use if you:
Have insulin dependent diabetes (type 1 diabetes mellitus)
Have diabetic ketoacidosis (a complication of diabetes with fatigue, nausea, frequent urination and muscular stiffness)
Are in a diabetic coma
Have serious problems with adrenal glands or pituitary glands
Have porphyria (abdominal pain, mental confusion, anxiety, fits, muscle pain etc.)
Before taking AFDIEX 5MG, inform your doctor if you:
Are recovering from an injury, operation, infections with fever or stress.
Are weak. You are more likely to suffer from hypoglycemia (low blood-sugar levels)
Have lactose deficiency (you are unable to digest milk or milk product)
Have G6PD- deficiency (enzyme which protects red blood cells)
Suffer from hormone induced disorders (of the thyroid glands, of the pituitary gland or adrenal cortex)
Use in pediatrics:
AFDIEX 5MG is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking it.
Use in geriatrics:
AFDIEX 5MG should be used with caution in elderly patients above 65 years of age as they are sensitive to hypoglycemic action. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Consult your doctor before taking AFDIEX 5MG.
INTERACTIONS
A. Drug - Drug interactions:
Before taking AFDIEX 5MG, inform your doctor if you are taking any of the following medicines:
To treat pain and inflammation (Ex. phenylbutazone, glucocorticoids, azopropazone, oxyphenbutazone, aspirin)
For diabetes mellitus (Ex. insulin or metformin)
To support muscle build up (anabolics)
To prevent blood clotting (warfarin)
To reduce weight (fenfluramine)
To treat depression (Ex. fluoxetine, MAO inhibitors)
To treat gout (allopurinol, probenecid, sulfinpyrazone)
To treat cancer (Ex. cyclophosphamide, ifosfamide, trofosfamide)
To treat bacterial, fungal infections (tetracyclines, chloramphenicol, fluconazole, miconazole, quinolones, clarithromycin)
To treat hay fever (tritoqualine)
To increase circulation (pentoxifylline)
To treat urinary infections (such as sulfonamides)
Containing female sex hormones (estrogens, progestogens)
To treat high blood pressure (bosentan, thiazide diuretics, betablockers, clonidine, guanethidine, diazoxide, glucagon, reserpine, ACE inhibitors), antiarrhythmic agents used to control abnormal heartbeat (disopyramide)
To stimulate the thyroid gland (levothyroxine)
To treat severe mental disorders (Ex. chlorpromazine, phenothiazine derivatives)
Adrenaline and sympathomimetics
To treat high cholesterol levels (Ex. nicotinic acid, fibrates)
To treat constipation (laxatives)
To treat fits (phenytoin)
For nervousness, sleep problems (barbiturates)
To treat infections, tuberculosis (rifampicin)
For increased pressure in the eye (azetazolamide)
Medicines used for stomach ulcers
Overdosage:
If you or anyone else accidentally take too much of AFDIEX 5MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are characterized by faintness, feeling sick, cold sweats and palpitations.
SYNOPSIS
Drug
:
Glibenclamide
Pharmacological Category
:
Sulfonylureas
Therapeutic Indication
:
Type 2 diabetes mellitus
Dosage Forms
:
Tablet
MORE INFORMATION
Keep AFDIEX 5MG out of reach of children
Store at 25°C
