<p>&nbsp;</p>

<p>BREASTFEEDING</p>

<p>BUPRON XL 300MG TABLET should be used with caution in breastfeeding women only if it is clearly necessary as the medicine may pass through breast milk. Consult your doctor before taking BUPRON XL 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/driving_and_using_machines.jpg" /></p>

<p>DRIVING AND USING MACHINES</p>

<p>Do not drive/operate machines if your ability to drive/operate machines is impaired after taking BUPRON XL 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/alcohol.jpg" /></p>

<p>ALCOHOL</p>

<p>Avoid consumption of alcohol while taking BUPRON XL 300MG TABLET since it may alter the effect of the medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/kidney.jpg" /></p>

<p>KIDNEY</p>

<p>BUPRON XL 300MG TABLET should be used with caution in patients with kidney problems such as renal impairment<strong>.&nbsp;</strong>Consult your doctor before taking the medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/liver.jpg" /></p>

<p>LIVER</p>

<p>BUPRON XL 300MG TABLET should be used with extreme caution in patients with liver problems such as severe hepatic cirrhosis, mild to moderate hepatic impairment. Consult your doctor before taking the medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/allergy.jpg" /></p>

<p>ALLERGY</p>

<p>Do not take BUPRON XL 300MG TABLET if you are allergic to Bupropion, and/or any other ingredients in this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/heart_disease.jpg" /></p>

<p>HEART DISEASE</p>

<p>BUPRON XL 300MG TABLET should be used with caution in patients with heart problems such as heart attack, unstable heart disease, left ventricular dysfunction. Consult your doctor before taking BUPRON XL 300MG TABLET.</p>

<h2>OTHERS</h2>

<p>BUPRON XL 300MG TABLET is not recommended for use if you:</p>

<ul>
<li>Have/had a seizure disorder/epilepsy</li>
<li>Have/ had an eating disorder such as anorexia nervosa (an eating disorder that causes people to get obsessed about weight on what they eat)/bulimia (an eating disorder in which you consume a large quantity of food in one sitting).</li>
</ul>

<p>Before taking BUPRON XL 300MG TABLET, inform your doctor if you:</p>

<ul>
<li>Are a diabetic&nbsp;</li>
<li>Have ever had depression/other mental health problems, suicidal thoughts</li>
<li>Have had a head injury</li>
<li>Have a tumor in brain/spinal cord</li>
<li>Have high blood pressure</li>
</ul>

<p><strong>Use in Pediatrics:</strong></p>

<p>BUPRON XL 300MG TABLET is generally not recommended for use in children and adolescents (aged below 18 years) unless it is clearly considered necessary. Your doctor might monitor the effects of the drug for any possible side effects, especially on suicidality, and unusual changes in behaviour during the initial few months of the course of treatment. Consult your doctor before administering the medicine to the child.</p>

<p><strong>Use in Geriatrics:</strong></p>

<p>BUPRON XL 300MG TABLET should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking BUPRON XL 300MG TABLET.</p>

<h2>INTERACTIONS</h2>

<p><strong>A. Drug-Drug Interactions:</strong></p>

<p>Before taking BUPRON XL 300MG TABLET, inform your doctor, if you are taking any of the following medicine:</p>

<ul>
<li>Zyban (medicine used to help people stop smoking)</li>
<li>Monoamine oxidase inhibitor (medicine used for depression) Ex. phenelzine sulfate, tranylcypromine sulfate, isocarboxazid</li>
<li>Insulin/other medicines to control your blood sugar (Ex.glimepiride,gliclazide, glipizide)</li>
</ul>

<p><strong>Overdosage:</strong></p>

<p>If you or anyone else accidentally takes too much of BUPRON XL 300MG TABLET, contact your doctor immediately or go to a hospital straight away. Symptoms of overdose are seizure, hallucinations, loss of consciousness, sinus tachycardia (fast heartbeat), arrhythmias (irregular heartbeat), fever, muscle rigidity, rhabdomyolysis (muscle death), low blood pressure, stupor (unconsciousness), coma, and respiratory failure.</p>

<h2>SYNOPSIS</h2>

<table border="0" cellpadding="1" cellspacing="1">
<tbody>
<tr>
<td><strong>Drug</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Bupropion</td>
</tr>
<tr>
<td><strong>Pharmacological Category</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Antidepressants</td>
</tr>
<tr>
<td><strong>Therapeutic Indication</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Major depressive disorder,&nbsp;seasonal affective disorder</td>
</tr>
<tr>
<td><strong>Dosage Forms</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Tablet</td>
</tr>
</tbody>
</table>

<h2>MORE INFORMATION</h2>

<ul>
<li>Keep BUPRON XL 300MG TABLET out of reach in children</li>
<li>Store BUPRON XL 300MG TABLET at room temperature</li>
</ul>

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