<p>&nbsp;</p>

<p>BREASTFEEDING</p>

<p>DILEX CHRONO 300MG TABLET is not recommended for use by breastfeeding mothers, as it may pass through breastfed milk. Consult your doctor before taking DILEX CHRONO 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/driving_and_using_machines.jpg" /></p>

<p>DRIVING AND USING MACHINES</p>

<p>Avoid driving or operating machines, if you feel drowsy or sleepy after taking DILEX CHRONO 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/alcohol.jpg" /></p>

<p>ALCOHOL</p>

<p>Avoid consuming alcohol while taking DILEX CHRONO 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/kidney.jpg" /></p>

<p>KIDNEY</p>

<p>DILEX CHRONO 300MG TABLET should be used with caution in patients with kidney diseases. Consult your doctor for advice before taking DILEX CHRONO 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/liver.jpg" /></p>

<p>LIVER</p>

<p>DILEX CHRONO 300MG TABLET is not recommended for use in patients with liver problems or any family history of liver problems such as severe hepatic dysfunction, particularly due to some medicine. Consult your doctor for advice before taking DILEX CHRONO 300MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/allergy.jpg" /></p>

<p>ALLERGY</p>

<p>DILEX CHRONO 300MG TABLET is not recommended for use if you are allergic to Valproic acid, Sodium valproate or any other ingredients in this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/lungs.jpg" /></p>

<p>LUNGS</p>

<p>DILEX CHRONO 300MG TABLET should be used with caution in patients with lung diseases such as chronic obstructive pulmonary disease. Consult your doctor for advice before taking DILEX CHRONO 300MG TABLET.</p>

<h2>OTHERS</h2>

<p>DILEX CHRONO 300MG TABLET is not recommended for use if you:</p>

<ul>
<li>Have porphyria (a hereditary disease that affects the skin or nervous system)</li>
<li>Have blood coagulation or clotting disorders such as deep vein thrombosis, pulmonary embolism&nbsp;</li>
<li>Have pancreatic diseases</li>
<li>Have signs of urea cycle disorder (excessive ammonia build-up in the body) such as loss of appetite, vomiting and lethargy that causes excessive ammonia builds up in the body</li>
<li>Have a genetic disorder called Alpers-Huttenlocher syndrome (a progressive, neurodevelopmental syndrome characterized by three co-occurring clinical symptoms which are psychomotor regression (dementia); seizures; and liver disease)</li>
</ul>

<p>Before taking DILEX CHRONO 300MG TABLET, inform your doctor if you:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<ul>
<li>Have diabetes</li>
<li>Are scheduled for surgery such as dental surgery</li>
<li>Have systemic lupus erythematosus (a disease of the immune system that affects bones, joints and body organs)</li>
<li>Have a certain brain disease or any metabolic condition affecting your brain such as hypoglycaemic encephalopathy</li>
<li>Have a deficiency condition such as carnitine palmitoyl transferase type II deficiency (a condition that prevents the body from using certain fats for energy, particularly during periods without food)</li>
</ul>

<p><strong>Use in Paediatrics:</strong></p>

<p>DILEX CHRONO 300MG TABLET should be used with caution in children (below 2 years of age). Consult your doctor before taking DILEX CHRONO 300MG TABLET.</p>

<p><strong>Use in Geriatrics:</strong></p>

<p>DILEX CHRONO 300MG TABLET should be used with caution in elderly patients (aged above 68 years). Consult your doctor before taking DILEX CHRONO 300MG TABLET.</p>

<h2>INTERACTIONS</h2>

<p><strong>A. Drug-Drug Interactions:</strong></p>

<p>Before taking DILEX CHRONO 300MG TABLET, inform your doctor, if you are taking any of the following medicine:</p>

<ul>
<li>Medicines used to treat depression or Parkinson&rsquo;s disease, such as monoamine oxidase inhibitors (MAOI) Ex. selegiline, phenelzin</li>
<li>Medicines used to treat emotional and mental conditions Ex. diazepam, olanzapine</li>
<li>Medicine used to treat HIV infection Ex. zidovudine</li>
<li>Medicines used for thinning the blood Ex. warfarin</li>
<li>Other medicines used to treat epilepsy Ex. phenytoin, phenobarbital, carbamazepine, primidone, rufinamide, topiramate, acetazolamide, lamotrigine and felbamate</li>
<li>Medicines used to treat pain and inflammation such as salicylates Ex. aspirin</li>
<li>Medicines used to prevent and treat malaria Ex. mefloquine, chloroquine</li>
<li>Medicines used to treat stomach ulcers Ex. cimetidine</li>
<li>Antibiotics or medicines used to treat bacterial infections such as carbapenem agents Ex. imipenem, meropenem, ertapenem, erythromycin</li>
<li>Medicines used to lower blood cholesterol Ex. cholestyramine</li>
<li>Medicines used to treat tuberculosis Ex. rifampicin</li>
<li>Medicines used to treat cancer Ex. temozolomide</li>
<li>Medicines used to treat bleeding in the brain Ex. nimodipine</li>
<li>Medicines used to anaesthetise Ex. Propofol</li>
<li>Medicines used for birth control Ex. oestrogen-containing products</li>
<li>Medicines used to treat pain and fever Ex. metamizole</li>
</ul>

<p><strong>Overdosage</strong></p>

<p>If you or anyone else accidentally takes too much of DILEX CHRONO 300MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include nausea, vomiting, headache, blurred vision, dizziness, poor reflexes, confusion, memory loss, tiredness, muscle weakness, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing or shortness of breath or chest pain.</p>

<h2>SYNOPSIS</h2>

<table border="0" cellpadding="1" cellspacing="1">
<tbody>
<tr>
<td><strong>Drug</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Sodium valproate, Valproic acid</td>
</tr>
<tr>
<td><strong>Pharmacological Category</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Anticonvulsants/Antiepileptics</td>
</tr>
<tr>
<td><strong>Therapeutic Indication</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Epilepsy, Bipolar disorder</td>
</tr>
<tr>
<td><strong>Dosage Forms</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Tablet</td>
</tr>
</tbody>
</table>

<h2>MORE INFORMATION</h2>

<ul>
<li>Keep DILEX CHRONO 300MG TABLET out of reach from children</li>
<li>Store DILEX CHRONO 300MG TABLET at room temperature</li>
</ul>

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